TGF beta 1 is a protein that plays an important role in many biological processes. It is an important regulator of cell growth and differentiation, which is particularly relevant in medical research. Our TGF Beta 1 solutions are highly purified and of the highest quality, making them ideal for research.
Protein: pro-TGF-beta 1, His-tag
Protein: pro-TGF-beta 1, His-tag
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pro-TGF-beta 1, His-tag is a recombinant protein designed to facilitate research in the field of Transforming Growth Factor beta 1 (TGF-beta 1). This His-tagged protein offers excellent solubility in a variety of buffers for both in vitro and in vivo applications.
Protein: pro-TGF-beta 1, His-tag (~ 44.9 kDa)
Uniprot#: P01137
Sequence: MELVKRKRIEAIRGQILSKLRLASPPSQGEVPPG
PLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVETHNEIYDKFKQSTHSI
YMFFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNNSWRYLSNRLLAPSD
SPEWLSFDVTGVVRQWLSRGGEIEGFRLSAHCSCDSRDNTLQVDINGFTTGRRGDLATIH
GMNRPFLLLMATPLERAQHLQSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWI
HEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVG
RKPKVEQLSNMIVRSCKCS
Methionine at pos. 1 present due to cloning constraints, N-terminal His-tag
not shown in sequence.
Source: Recombinantly expressed in HEK293 cells.
Tag(s): His-tag, N-terminal
Purification: Purified by affinity chromatography and subsequent buffer exchange.
Formulation: PBS; pH 7.4.
Liquid, stored and shipped at -80 °C.
Purity: > 95 % (will be determined by densitometry of Coomassie stained gel, example next page)
Concentration: Will be determined by BCA-Assay.
Long-term storage: No recommendations.
Comment: Pro-TGF-beta 1 consists of the latency associated peptide (LAP) and the mature transforming growth factor (TGF)-beta 1 together forming the small latent complex (SLC). This results in three distinct protein bands in SDS-PAGE as illustrated on page 2.Share
